The demonstrators outnumbered police officers who had been deployed to protect the premises.
They carted away valuables from the building including iron sheets used to fence the compound.
A rowdy crowd of anti-government protesters has torched offices belonging to President William Ruto's United Democratic Alliance (UDA) party in Karemo area, Siaya County.
This is the second UDA office to be set ablaze during protests after angry demonstrators broke into, vandalised and eventually torched offices belonging to the party in Kisumu last Monday.