Wine's lawyer Anthony Wameli said his client was seized on Wednesday at the offices of his opposition party, the National Unity Platform.
Earlier in the day, Wine tweeted that the police and military had "broken into offices and taken away valuable documents".
Ugandan security forces detained pop star-turned-politician Bobi Wine on Wednesday during a raid of the presidential aspirant's offices in the capital Kampala, his lawyer said.
An opposition MP whose real name is Robert Kyagulanyi, Wine has previously been arrested numerous times as he has rattled the ruling party of President Yoweri Museveni, who has ruled the East African nation since 1986.